Author
University of North Carolina at Chapel HillORCID 0000-0001-7299-9608Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Liujiang Song, Tomoko Hasegawa, Nolan J Brown…·Matthew Louis Hirsch
This study evaluates a rationally designed ITR that reduces toxicity and transduction restriction in hESCs while maintaining gene delivery efficiency.
Tierney B. Daw, Hala G. El-Nahal, Michele A. Basso…·Martin O. Bohlen
The paper compares epifluorescence, immunofluorescence, and immunohistochemistry for assessing viral-mediated gene expression in macaques, finding that the latter two methods detect more transduced neurons and provide better visualization.
Junping Zhang, Ping Guo, Xiangping Yu…·Weidong Xiao
The paper identifies satellite subgenomic particles (SBGs) as regulators of AAV life cycle by balancing gene expression and packaging efficiency.