Molecular BiologybioRxivPreprint
Adeno-Associated Virus (AAV) Synthetic Inverted Terminal Repeats Enhance Tissue-Specific Transduction and Alter the Vector Induced Stress Response
Tomoko Hasegawa, Naveen Vridhachalam, Ethan Sud Nikolai…·Matthew Louis Hirsch
This study shows that synthetic AAV inverted terminal repeats improve tissue-specific transduction and reduce cellular stress response in multiple tissues.
DOI 10.64898/2026.07.10.737493