Joni Herttuainen

This study shows that current mechanisms for orientation selectivity in the visual cortex fail in realistic models, suggesting homeostatic plasticity may be necessary.

The paper creates a detailed computational model of rat somatosensory cortex anatomy, including 4.2 million neurons and 14.2 billion synapses, and identifies limitations in connectivity prediction from morphology.

The paper presents a large-scale biophysically detailed model of somatosensory cortex to simulate and validate cortical dynamics and experimental results.

The paper presents a full-scale in silico model of rat hippocampal CA1 integrating diverse experimental data and validates it through simulations of theta rhythm and other experiments.

The paper develops a computational model of mouse thalamoreticular microcircuitry to study sensory enhancement and sleep spindle properties, revealing mechanisms of network-level activity across brain states.

The paper quantifies neuromodulatory fiber length and varicosity density in rat somatosensory cortex and predicts their effects on network activity.