Hugo Dictus

This study shows that current mechanisms for orientation selectivity in the visual cortex fail in realistic models, suggesting homeostatic plasticity may be necessary.

The paper creates a detailed computational model of rat somatosensory cortex anatomy, including 4.2 million neurons and 14.2 billion synapses, and identifies limitations in connectivity prediction from morphology.

The paper synthesizes cortical dendrites using a topological descriptor to create statistically similar digital reconstructions, enabling the study of neuronal morphology and brain function.