Author

Tie Shen

Guizhou Normal UniversityORCID 0000-0001-7313-3494Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Chaowei ShiiD· 1 shared Dan Su· 1 shared Hongfeng WangiD· 1 shared Huanyu LiiD· 1 shared Juan LiiD· 1 shared Shengqi XiangiD· 1 shared Yize Zhang· 1 shared Zheng YingiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperBiochemistry

Chaowei ShiORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintOct 13, 2026

Cooperative IDR-folded domain interplay governs HP1α phase separation and underlies biphasic regulation by pathogenic poly-PR

Yize Zhang, Dan Su, Huanyu Li…·Shengqi Xiang

This study shows that HP1α phase separation is driven by interactions between intrinsically disordered regions and folded domains, not just IDRs alone, and reveals how poly-PR affects this process in a concentration-dependent manner.

DOI 10.64898/2026.10.10.758178

humanexperimental assay

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