ImmunologybioRxivPreprint
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A surviving beta cell subpopulation enriched in patients with T1D
Maxwell Spurrell, Zuzana Tobiásová, Jordan S. Pober…·Kevan C. Herold
Regulon-based clustering of islet scRNA-seq finds an IRF1-high, cytokine-driven beta cell state with reduced identity and autoantigen genes, enriched in type 1 diabetes donors.