Author
Broad InstituteORCID 0000-0003-2856-8602Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Ragnhild Laursen, Han Chen, Jack Demaray…·Barbara Elizabeth Engelhardt
The paper introduces NNMF, a spatially-aware method for analyzing spatial transcriptomics data, identifying multicellular patterns and spatially-variable genes in large datasets.
Han Chen, Madhavan S. Venkatesh, Javier Gómez Ortega…·Christina V. Theodoris
The paper develops a multi-task learning approach to create context-specific gene network representations, applying it to colorectal tumors to predict therapeutic targets.
Michael R. Filbin, Arnav Mehta, Alexis M. Schneider…·Marcia B. Goldberg
The paper uses plasma proteomics to identify tissue-specific cell death and cell-cell interaction mediators in severe COVID-19 patients, linking them to survival outcomes and viral infection effects.