Author

DEBORAH HEYDENBURG FULLER

University of WashingtonORCID 0000-0001-7315-2441Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Deborah Heydenburg Fuller1 paper · University of Washington;

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:non-human primate· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Solomon Wangari· 2 shared Thomas B. LewisiD· 2 shared Alexandra N. Christodoulou· 1 shared Amanda LiiD· 1 shared Andrew E VoiD· 1 shared Anne PinkiD· 1 shared Audrey E. BaldessariiD· 1 shared Audrey Germond· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersSystems Biology

Solomon Wangari

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3 papers

Recent·Most cited

Systems BiologyScience AdvancesPeer-reviewedOct 9, 2026

Maternal Influenza A Virus Infection Induces Antiviral and Immune Dysregulation in the Placenta and Fetus Without Vertical Transmission

Orlando Cervantes, Sidney C. Sun, Hazel Huang…·Kristina M. Adams Waldorf

Maternal influenza A virus infection in pregnant pigtail macaques dysregulates placental and fetal immunity, with disease severity correlating strongly with fetal, but not placental, immune perturbations.

DOI 10.1126/sciadv.aee9861

non-human primatebulk RNA-seq

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BiochemistrybioRxivPreprintMay 2, 2026

Integrin-independent Tie2 activation using de novo designed proteins

Clara McCurdy, Yan Ting Zhao, Saurav Kumar…·Hannele Ruohola‐Baker

This paper designs a de novo Tie2 binder that activates the Angiopoietin-Tie2 pathway without integrin engagement, showing improved therapeutic potential in a mouse model of ARDS.

DOI 10.64898/2026.05.01.718274

mousedeep learning

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ImmunologyFrontiers in ImmunologyPeer-reviewedMar 4, 2025

Chronic innate immune impairment and ZIKV persistence in the gastrointestinal tract during SIV infection in pigtail macaques

Jennifer Tisoncik-Go, Thomas B. Lewis, Leanne S. Whitmore…·Megan A. O’Connor

This study investigates how SIV-induced immunosuppression affects ZIKV replication and persistence in pigtail macaques, finding increased viral persistence and chronic immune activation in the gastrointestinal tract.

2 citations

non-human primateexperimental assay

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