Monika Moissidis

Fate mapping in mouse shows two separate MGE radial glia pools; the later pool uses temporal cohorts of fate-restricted basal intermediate progenitors to amplify and diversify cortical interneurons.

This study identifies a molecular switch driven by neuronal activity and PGC-1 that promotes the maturation of parvalbumin interneurons during postnatal development.

The paper identifies somatostatin-expressing interneurons as critical for controlling the timing of developmental desynchronization in cortical networks.