Dynamic control of pathway expression with riboregulated switchable feedback promoters
Cameron J. Glasscock, John Tyler Lazar, Bradley Walters Biggs, Jack H. Arnold, Min‐Kyoung Kang, Danielle Tullman‐Ercek, Keith E. J. Tyo, Julius B. Lucks
The paper introduces a new gene expression cassette called a riboregulated switchable feedback promoter (rSFP) to dynamically control gene expression in metabolic engineering, achieving higher titers in a Taxol precursor biosynthesis pathway.
bioRxiv · Jan 23, 2019 · PreprintSynthetic Biology