Author

Negar Safinianaini

Aalto UniversityORCID 0000-0001-7346-8761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:clustering· 2 Organism:human· 2 Approach:variational autoencoder· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Alexandra Gorbonos· 1 shared Andrew J. L. RothiD· 1 shared Camila P. E. de SouzaiD· 1 shared Hazal KoptageliD· 1 shared Hosein ToosiiD· 1 shared Jens LagergreniD· 1 shared Kristiina RajamäkiiD· 1 shared Lauri A. AaltoneniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Alexandra Gorbonos

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2 papers

Recent·Most cited

BioinformaticsCommunications BiologyPeer-reviewedJul 6, 2026

OMIDIENT: Multiomics Integration for Cancer by Dirichlet Auto-Encoder Networks

Negar Safinianaini, Niko Välimäki, Roman Bresson…·Pekka Marttinen

OMIDIENT is a multi-omics integration method that uses Dirichlet auto-encoders to improve clustering, classification, and data reconstruction across cancer types.

DOI 10.1038/s42003-026-10578-1

humanDNA methylation

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BioinformaticsComputational Biology and ChemistryPeer-reviewedOct 23, 2024

CopyMix: Mixture Model Based Single-Cell Clustering and Copy Number Profiling using Variational Inference

Negar Safinianaini, Camila P. E. de Souza, Andrew J. L. Roth…·Jens Lagergren

CopyMix jointly infers cell clusters and copy number profiles from single-cell DNA sequencing data, avoiding clustering artifacts and parameter tuning.

3 citations

humanscRNA-seq

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