Author

Kristiina Rajamäki

University of HelsinkiORCID 0000-0001-5151-1220Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1 Assay:DNA methylation· 1 Assay:multiome· 1

Frequent Co-Authors

Airi E. Jartti· 1 shared Alexandra Gorbonos· 1 shared Antti Väänänen· 1 shared Dan NordströmiD· 1 shared Janna SaarelaiD· 1 shared Kari K. EklundiD· 1 shared Lauri A. AaltoneniD· 1 shared Luca TrottaiD· 1 shared

Activity by Year

2018-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Airi E. Jartti

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2 papers

Recent·Most cited

BioinformaticsCommunications BiologyPeer-reviewedJul 6, 2026

OMIDIENT: Multiomics Integration for Cancer by Dirichlet Auto-Encoder Networks

Negar Safinianaini, Niko Välimäki, Roman Bresson…·Pekka Marttinen

OMIDIENT is a multi-omics integration method that uses Dirichlet auto-encoders to improve clustering, classification, and data reconstruction across cancer types.

DOI 10.1038/s42003-026-10578-1

humanDNA methylation

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Molecular BiologyRMD OpenPeer-reviewedOct 1, 2018

Haploinsufficiency of A20 impairs protein-protein interactome and leads into caspase-8-dependent enhancement of NLRP3 inflammasome activation

Kristiina Rajamäki, Salla Keskitalo, Mikko R. J. Seppänen…·Markku T Varjosalo

This study identifies a novel mutation in A20 causing haploinsufficiency and shows it impairs the protein-protein interactome, leading to enhanced NLRP3 inflammasome activation through caspase-8.

34 citations

humanproteomics

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