Author

Nuno R. dos Santos

Universidade do PortoORCID 0000-0001-7347-2592Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:flow cytometry· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

João L. PereiraiD· 2 shared Francisca Ferreira· 1 shared Ivette Pacheco-LeyvaiD· 1 shared Marina BaessaiD· 1 shared Telmo A. CatarinoiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 7 mutual co-author links

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2 shared papersCancer Biology

João L. PereiraORCID

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2 papers

Recent·Most cited

Cancer BiologyJournal of Leukocyte BiologyPeer-reviewedNov 21, 2024

Transgenic αβ TCR tonic signaling is leukemogenic while strong stimulation is leukemia-suppressive

Telmo A. Catarino, Ivette Pacheco-Leyva, Marina Baessa…·Nuno R. dos Santos

This study shows that transgenic β TCR expression in mice causes T-ALL, but strong TCR stimulation suppresses it, highlighting a dual role of TCR signaling in leukemia.

1 citation

mousebulk RNA-seq

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Cancer BiologyHematological OncologyPeer-reviewedFeb 28, 2024

Antibody targeting of surface PSGL-1 glycoprotein leads to lymphoma apoptosis and tumorigenesis inhibition

João L. Pereira, Francisca Ferreira, Nuno R. dos Santos

This study shows that targeting PSGL-1 with an antibody induces apoptosis in lymphoma cells and inhibits tumorigenesis in some models.

8 citations

humanflow cytometry

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