Author

Ivette Pacheco-Leyva

Universidade do PortoORCID 0000-0003-3006-2264Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

João L. PereiraiD· 1 shared Marina BaessaiD· 1 shared Nuno R. dos SantosiD· 1 shared Telmo A. CatarinoiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

João L. PereiraORCID

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1 paper

Recent·Most cited

Cancer BiologyJournal of Leukocyte BiologyPeer-reviewedNov 21, 2024

Transgenic αβ TCR tonic signaling is leukemogenic while strong stimulation is leukemia-suppressive

Telmo A. Catarino, Ivette Pacheco-Leyva, Marina Baessa…·Nuno R. dos Santos

This study shows that transgenic β TCR expression in mice causes T-ALL, but strong TCR stimulation suppresses it, highlighting a dual role of TCR signaling in leukemia.

1 citation

mousebulk RNA-seq

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