ImmunologyScience Translational MedicinePeer-reviewed
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Vaccination with mRNA-encoded membrane-bound HIV Envelope trimer induces neutralizing antibodies in animal models
Parham Ramezani-Rad, Christopher A. Cottrell, Ester Marina-Zárate…·William R. Schief
Membrane-bound BG505 MD39.3 Env trimer delivered as mRNA-LNP reduced base-directed antibody responses in rabbits and macaques and elicited neutralizing antibodies, with memory B cell responses documented in macaques.
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