Author

Andy S. Tran

Scripps Research InstituteORCID 0009-0004-0508-6015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Organism:rat· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Andrew B. WardiD· 4 shared Gabriel OzorowskiiD· 4 shared Christopher A. CottrelliD· 3 shared Darrell J. IrvineiD· 3 shared Diane G. CarnathaniD· 3 shared Guido SilvestriiD· 3 shared Shane CrottyiD· 3 shared Arpan PradhaniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Andrew B. WardORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Sequential vaccination matures VRC01-class HIV-1 neutralizing antibodies in humans

Tom G. Caniels, Madhu S. Prabhakaran, Sashank Agrawal, Kellie J. MacPhee, Rhianna Bronson, Weiwei Wu, Eva I.M. Schumacher, Swastik Phulera, Katrina G. Millard, Deanna Dong, Martina Turroja, Aimee A. Desrosiers, Jeffrey Michael Bethony, Elissa M. Malkin, Annelou van der Veen, , Rogier W. Sanders

This study shows that sequential vaccination can mature VRC01-class B cells into antibodies that neutralize a broad range of HIV-1 viruses.

bioRxiv · Oct 26, 2026 · PreprintImmunology

Germinal centers can persist for up to one year with declining somatic hypermutation and ongoing plasma cell output

Henry J. Sutton, Ester Marina-Zárate, Tasha K. Altheide, Arpan Pradhan, Amit A. Upadhyay, Iszac Burton, Michael Bick, Agnes A. Walsh, Mariane B. Melo, Jenny Tran, Nicole Phelps, Danny Lu, Diana Goodwin, Wen-Hsin Lee, Kipchoge N. Randall, , Shane Crotty

This study tracks germinal center responses in rhesus macaques over a year, showing prolonged GCs with declining SHM and ongoing plasma cell production.

bioRxiv · Oct 16, 2026 · PreprintImmunology

Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques

Payal P. Pratap, Christopher A. Cottrell, James Quinn, Diane G. Carnathan, Daniel L. V. Bader, Andy S. Tran, Chiamaka A. Enemuo, Julia T. Ngo, Sara T. Richey, Hongmei Gao, Xiaoying Shen, Kelli Greene, Jonathan Hurtado, Katarzyna Kaczmarek Michaels, Elana Ben‐Akiva, , Andrew B. Ward

This study shows that targeting the conserved HIV fusion peptide with modified Env immunogens in rhesus macaques can focus immune responses on neutralizing epitopes.

npj Vaccines · Aug 20, 2025Peer-reviewedImmunology

Vaccination with mRNA-encoded membrane-bound HIV Envelope trimer induces neutralizing antibodies in animal models

Parham Ramezani-Rad, Christopher A. Cottrell, Ester Marina-Zárate, Alessia Liguori, Elise Landais, Jonathan L. Torres, Amber Myers, Jeong Hyun Lee, Sabyasachi Baboo, Claudia T. Flynn, Katherine R. McKenney, Eugenia Salcedo, Xiaoya Zhou, Oleksandr Kalyuzhniy, Erik Georgeson, , William R. Schief

Membrane-bound BG505 MD39.3 Env trimer delivered as mRNA-LNP reduced base-directed antibody responses in rabbits and macaques and elicited neutralizing antibodies, with memory B cell responses documented in macaques.

Science Translational Medicine · Jul 30, 2025Peer-reviewedImmunology✦ In-depth digest