Andrew Retter

The paper uses ATAC-Seq to study chromatin accessibility in neutrophils stimulated with inflammatory factors, finding stimulus-specific programs linked to sepsis transcriptional states.

This study compares chromatin accessibility changes during NET formation in whole blood versus isolated neutrophils, finding that whole blood responses show stronger immune pathway activation.

This paper introduces a novel ex-vivo whole blood model for inducing NETosis using physiological triggers, showing that three factors are required and responses vary between donors.