Author

Patrick Connerty

UNSW SydneyORCID 0000-0001-7394-9282Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

Frequent Co-Authors

Abdul MannaniD· 1 shared Ali AfrasiabiiD· 1 shared Alicia M. DouglasiD· 1 shared Andrew H. WeiiD· 1 shared Anoop Kumar EnjetiiD· 1 shared Brett NixoniD· 1 shared Bryce C. ThomasiD· 1 shared Cara E. ToscaniD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Abdul MannanORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 26, 2024

Adaptive resistance to FLT3 inhibitors is potentiated by ROS-driven DNA repair signalling

Dilana Elisabeth Staudt, Zacary P. Germon, Abdul Mannan…·Matthew D. Dun

This study identifies ATM-driven DNA repair and ROS addiction as mechanisms of resistance to FLT3 inhibitors in AML and shows ATM inhibition can overcome resistance in vitro and in vivo.

DOI 10.1101/2024.07.26.605229

humanbulk RNA-seq

Molecular BiologybioRxivPreprintApr 17, 2024

Genome-Wide CRISPR-Cas9 Screening Identifies a Synergy between Hypomethylating Agents and SUMOylation Blockade in MDS/AML

Peter Truong, Sylvie Shen, Swapna Mahurkar Joshi…·John E. Pimanda

This study identifies a synergy between hypomethylating agents and SUMOylation blockade in MDS/AML using CRISPR-Cas9 screening, showing improved therapeutic outcomes in xenograft models.

DOI 10.1101/2024.04.17.589858

humanwhole-genome sequencing