Author

Fawad Ur Rehman

Aga Khan UniversityORCID 0000-0001-7403-0040Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 3 Approach:experimental assay· 3 Organism:human· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Irfan HussainiD· 3 shared Afsar Ali MianiD· 2 shared Ambrin FatimaiD· 2 shared Farhatullah SyediD· 2 shared Kainaat Mumtaz· 2 shared Muhammad Jameel· 2 shared Anas Mohammed Alazami· 1 shared Anwar AlamiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersCell Biology

Irfan HussainORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell BiologybioRxivPreprintSep 24, 2026

Prime Editing Corrects the HBB Codon 8/9 (+G) Mutation in Patient-Derived Induced Pluripotent Stem Cells and Restores β-Globin Expression in iPSC-Derived Erythroid Cells

Irfan Hussain, Kainaat Mumtaz, Maliha Javed…·Afsar Ali Mian

This study uses prime editing to correct the HBB c.27dupG mutation in patient-derived iPSCs and restores β-globin expression in erythroid cells.

DOI 10.64898/2026.09.22.753453

humanCRISPR screen

BioengineeringbioRxivPreprintJul 22, 2026

A TLS11a-decorated ionizable lipid nanoparticle platform and a multilevel-validated CRISPR LDLR-knockout HepG2 model for hepatocyte-preferential mRNA delivery

Irfan Hussain, Naji Kholaif, Raghad Alsultan…·Farhatullah Syed

The paper develops an LDLR-independent LNP platform for hepatocyte-targeted mRNA delivery and validates an LDLR-knockout HepG2 model for studying LDLR biology.

DOI 10.64898/2026.07.21.739738

humanCRISPR screen

Molecular BiologybioRxivPreprintNov 28, 2023

Prioritization of The Zinc finger domain within BCL11A gene by the Amelioration capability of hemoglobinopathies using CRISPR-Cas9 technology

Kainaat Mumtaz, Irfan Hussain, Fizza Iftikhar…·Afsar Ali Mian

This study uses CRISPR-Cas9 to investigate BCL11A zinc finger domains' role in gamma-globin regulation and hemoglobinopathy treatment, finding Znf4 deletion increases HbF levels.

DOI 10.1101/2023.11.28.568974

humanCRISPR screen