Author

Muhammad Jameel

Aga Khan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Afsar Ali MianiD· 2 shared Ambrin FatimaiD· 2 shared Fawad Ur RehmaniD· 2 shared Irfan HussainiD· 2 shared Kainaat Mumtaz· 2 shared Anwar AlamiD· 1 shared Farhatullah SyediD· 1 shared Fizza IftikhariD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCell Biology

Afsar Ali MianORCID

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2 papers

Recent·Most cited

Prime Editing Corrects the HBB Codon 8/9 (+G) Mutation in Patient-Derived Induced Pluripotent Stem Cells and Restores β-Globin Expression in iPSC-Derived Erythroid Cells

Irfan Hussain, Kainaat Mumtaz, Maliha Javed, Susheel Fatima, Hijab Zahra, Anwar Alam, Muhammad Jameel, Naveed Altaf Malik, Farhatullah Syed, Fawad Ur Rehman, Salman Kirmani, Ambrin Fatima, Afsar Ali Mian

This study uses prime editing to correct the HBB c.27dupG mutation in patient-derived iPSCs and restores β-globin expression in erythroid cells.

bioRxiv · Sep 24, 2026 · PreprintCell Biology

Prioritization of The Zinc finger domain within BCL11A gene by the Amelioration capability of hemoglobinopathies using CRISPR-Cas9 technology

Kainaat Mumtaz, Irfan Hussain, Fizza Iftikhar, Fawad Ur Rehman, Muhammad Jameel, Safana Farooq, Hammad Hassan, Ambrin Fatima, Oliver Gerhard Ottmann, Afsar Ali Mian

This study uses CRISPR-Cas9 to investigate BCL11A zinc finger domains' role in gamma-globin regulation and hemoglobinopathy treatment, finding Znf4 deletion increases HbF levels.

bioRxiv · Nov 28, 2023 · PreprintMolecular Biology