Author

Tristan W. Owens

University of California, San FranciscoORCID 0000-0001-7423-4879Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Assay:structural biology· 1

Frequent Co-Authors

David A. AgardiD· 1 shared James A. WellsiD· 1 shared Kaitlin SchaeferiD· 1 shared Trenton M. Peters-ClarkeiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBiochemistry

David A. AgardORCID

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1 paper

Recent·Most cited

BiochemistrybioRxivPreprintAug 28, 2026

Structural and mechanistic analyses reveal collaborative regulation of HSF1 by the Hsp70-Hsp90 chaperone systems

Tristan W. Owens, Kaitlin Schaefer, Trenton M. Peters-Clarke…·David A. Agard

This study reveals how HSF1 is regulated by Hsp70 and Hsp90 chaperones through structural and mechanistic analyses, showing Hsp90's role in maintaining HSF1 in a pre-activated state.

DOI 10.64898/2026.08.27.747592

structural biologyexperimental assay

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