Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewed
Development of an orally bioavailable mSWI/SNF ATPase degrader and acquired mechanisms of resistance in prostate cancer
Tongchen He, Caleb Cheng, Yuanyuan Qiao…·Arul M. Chinnaiyan
This paper develops an orally bioavailable PROTAC degrader of mSWI/SNF ATPases for prostate cancer and identifies resistance mechanisms through long-term treatment.