Massimo Bellato

This study uses CRISPR interference to reduce antibiotic resistance in E. coli by targeting resistance genes without causing mutations.

This study compares two synthetic quorum sensing circuit architectures and evaluates three QS inhibition strategies to understand their steady-state behavior and parameter thresholds for effective suppression.

This paper evaluates CRISPR interference as low burden logic inverters in synthetic circuits, demonstrating reduced metabolic load through in-vivo assays.

This paper introduces a dCas9 regulator that reduces competition among sgRNAs in CRISPRi circuits, enabling independent gene repression control.