Pharmacology & ToxicologyThe Journal of Infectious DiseasesPeer-reviewed
✦ In-depth digest
The kinetics of bedaquiline diffusion in tuberculous cavities opens a window for emergence of resistance.
Annamarie E. Bustion, Jacqueline P. Ernest, Firat Kaya…·Veronique Anne Dartois
Rabbit lesion microdissection and pharmacokinetic modeling show bedaquiline takes months to reach deep caseum and years to clear, while TBAJ-587 and TBAJ-876 shorten these windows.
10 citationstop 2%