Author

Neeraj Y. Saini

The University of Texas MD Anderson Cancer CenterORCID 0000-0001-7435-0933Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

Christopher R. FlowersiD· 2 shared Elizabeth J. ShpalliD· 2 shared Kartik Devashish· 2 shared Mark R. TanneriD· 2 shared Michael David JainiD· 2 shared Romil D. PateliD· 2 shared Sattva Swarup NeelapuiD· 2 shared Abdur RehmaniD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Christopher R. FlowersORCID

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3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 3, 2026

Microbial valerate is associated with CAR T dysbiosis and its supplementation enhances CAR T function in B-cell lymphoma

Lubna Rehman, Wenting Song, Abdur Rehman…·Neeraj Y. Saini

This study links low stool valerate to CAR T-cell dysfunction in B-cell lymphoma and shows valerate supplementation improves CAR T function.

DOI 10.64898/2026.09.01.748711

humanbulk RNA-seq

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GeneticsbioRxivPreprintSep 28, 2021

Clonal hematopoiesis is associated with increased toxicity in large B-cell lymphoma patients treated with chimeric antigen receptor T cell therapy

Neeraj Y. Saini, David M. Swoboda, Uri Greenbaum…·Koichi Takahashi

This study finds that clonal hematopoiesis mutations, particularly in DNMT3A, TET2, and ASXL1, are linked to increased toxicity in patients undergoing anti-CD19 CAR T-cell therapy for large B-cell lymphoma.

DOI 10.1101/2021.09.28.461858

humanwhole-exome sequencing

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GeneticsbioRxivPreprintAug 28, 2021

Vectofusin-1 based T-cell transduction approach for generating murine chimeric antigen receptor T-cells for cancer.

Romil D. Patel, Kartik Devashish, Shubhra Singh…·Neeraj Y. Saini

This study evaluates vectofusin-1 as a transduction enhancer for generating murine CAR-T cells, finding it comparable to Retronectin.

DOI 10.1101/2021.08.28.458011

mouseexperimental assay

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