Author
Wageningen University & ResearchORCID 0000-0001-7436-2221Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Kasper Arfman, Bas P.J. Janssen, Robin Romein…·Joris H. B. Sprakel
This study shows that MpARF2 forms nanoclusters that enable high-affinity, switch-like, and sequence-specific DNA binding, distinct from monomeric or condensate-based mechanisms.
Belén Adiego-Pérez, Demian Fluit, Christina Ludwig…·Lorenzo Olivi
This study investigates how titration of an active DnaA variant controls DNA replication in E. coli under different growth conditions, revealing limits and design principles for synthetic replication systems.
Lorenzo Olivi, Stephan Köstlbacher, Christina Ludwig…·Raymond H.J. Staals
This study investigates DnaA titration on the E. coli chromosome and shows it controls free DnaA levels in a growth rate-dependent manner, preventing re-initiation during slow growth.