The paper identifies gender-specific and gender-independent cytokine markers in urine from Ghanaian CKD patients, suggesting potential biomarkers for early detection.

Journal of Personalized Medicine · Dec 24, 2022Peer-reviewedMolecular Biology

Redefining Nephrotic Syndrome in Molecular Terms: Outcome-associated molecular clusters and patient stratification with noninvasive surrogate biomarkers

Laura Mariani, Sean F. Eddy, Sebastian Martini, Felix H. Eichinger, Brad A. Godfrey, Viji Nair, Sharon G. Adler, Gerry B. Appel, Ambarish M. Athavale, Laura M. C. Barisoni, Elizabeth Brown, Dan C. Cattran, Katherine M. Dell, Vimal Kumar Derebail, Fernando Custodio Fervenza, , Matthias Kretzler

The paper identifies high-risk nephrotic syndrome patients through transcriptome analysis and develops non-invasive biomarkers to predict disease progression.

bioRxiv · Sep 27, 2018 · PreprintSystems Biology

An eQTL landscape of kidney tissue in human nephrotic syndrome

Christopher E. Gillies, Rosemary K.B. Putler, Rajasree Menon, Edgar A. Otto, Kalyn Yasutake, Viji Nair, Paul Hoover, David Lieb, Shuqiang Li, Sean F. Eddy, Damian Fermin, Michelle T. McNulty, John R. Sedor, Katherine M. Dell, Marleen Schachere, , Cindy Roy

The paper identifies eQTLs in glomerular and tubulointerstitial kidney tissues from nephrotic syndrome patients, finds tissue-specific eQTLs, and integrates them with a GWAS to identify associated genes.

The American Journal of Human Genetics · Jul 26, 2018Peer-reviewedGenomics