Author

Natalia Ospina-Muñoz

University of Illinois Urbana-ChampaignORCID 0000-0001-7835-2602Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Bumsoo HaniD· 2 shared Abigail D. CoxiD· 1 shared Ahmadreza KashefiiD· 1 shared Aja A. PhaniD· 1 shared Bashar EmoniD· 1 shared Bennett D. ElzeyiD· 1 shared Claudius H. ConradiD· 1 shared Darbaz AdnaniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Bumsoo HanORCID

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2 papers

Recent·Most cited

Extravascular coagulation stabilizes pro-fibrotic stromal states via tumor-intrinsic PAR1 signaling in pancreatic ductal adenocarcinoma

Sae Rome Choi, Natalia Ospina-Muñoz, Hye‐ran Moon, Sagar M. Utturkar, Duy Do, Yun Chang, Xiaoping Bao, Abigail D. Cox, Timothy L. Ratliff, Claudius H. Conrad, Melissa L. Fishel, Matthew J. Flick, Nadia A. Lanman, Bennett D. Elzey, Bumsoo Han

This study identifies extravascular coagulation as a regulator of fibrotic stromal states in PDAC via tumor-intrinsic PAR1 signaling, showing PAR1 inhibition can reprogram the tumor-promoting stroma.

bioRxiv · Sep 3, 2026 · PreprintCancer Biology

Biomechanical 3D tumor models on a micro-milled high-throughput force sensor array

Bashar Emon, Ahmadreza Kashefi, Md Habibur Rahman, Darbaz Adnan, Natalia Ospina-Muñoz, Seamus Mellican, Sophia Santiago, William Cartwright Drennan, Md Saddam Hossain Joy, Aja A. Phan, Tasmia Afrin, Luca Spiro Santovito, Bumsoo Han, Kyle Christopher Smith, Faraz Bishehsari, Taher A. Saif

This paper introduces a 3D tumor model with a high-throughput biomechanical sensor array to better mimic tumor biology and drug responses compared to 2D cultures.

Biofabrication · Mar 17, 2026Peer-reviewedCancer Biology