Author

Jianchun Xiao

Johns Hopkins UniversityORCID 0000-0001-7463-6122Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:proteomics· 1

Frequent Co-Authors

Emily G. SeveranceiD· 1 shared Jing Huang· 1 shared Raphael P. ViscidiiD· 1 shared Ye Li· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperMicrobiology

Emily G. SeveranceORCID

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2 papers

Recent·Most cited

MicrobiologyScientific ReportsPeer-reviewedApr 22, 2026

Blockade of Tim-3 pathway in a mouse model of Toxoplasmosis: impact on brain leukocyte infiltration, parasite burden, and neuroinflammation

Raphael P. Viscidi, Jing Huang, Ye Li…·Jianchun Xiao

This study shows that blocking the Tim-3 pathway in a mouse Toxoplasma gondii infection model reduces parasite burden and increases immune response markers.

1 citation

mousebulk RNA-seq

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MicrobiologybioRxivPreprintApr 6, 2026

Differential Regulation of Hepatic Akt/mTOR Signaling During Acute and Chronic Toxoplasma gondii Infection in a Murine Model

Jianchun Xiao

This study examines how T. gondii infection modulates hepatic Akt/mTOR signaling during acute and chronic stages, revealing opposing effects on pathway activation and suppression.

DOI 10.64898/2026.04.06.716682

mouseproteomics

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