Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation
Pinar Cakmak, Jennifer H. Lun, Aakanksha Singh, Jadranka Macas, Jonathan Schupp, Jonas Schuck, Zeina Mahmoud, Miriam I. Köhler, Tatjana Starzetz, Michael C. Burger, Eike Steidl, Lucie Marie Hasse, Elke Hattingen, Karl Heinz Plate, Yvonne Reiss, Katharina Imkeller
The paper identifies tertiary lymphoid structures in gliomas as sites of immune response, showing they correlate with better survival and involve T and B cell clonal expansion and plasma cell formation.
Immunity · Oct 21, 2025Peer-reviewedImmunology