Jonas Schuck

The paper develops LongAIRR, a computational framework for spatially resolving adaptive immune receptor repertoires from long-read sequencing, improving consensus accuracy and enabling platform-agnostic analysis.

The paper identifies tertiary lymphoid structures in gliomas as sites of immune response, showing they correlate with better survival and involve T and B cell clonal expansion and plasma cell formation.

This paper introduces a workflow for allele-specific immune gene quantification in scRNA-seq data, validated across datasets and platforms.

This study shows that blocking ATP-to-adenosine enzymes and combining with radiotherapy improves anti-cancer immunity in brain metastases by altering immune cell populations and tumor inflammation.