Jadranka Macas

Benchmarking cell-type deconvolution in cross-platform transcriptomic data

This study benchmarks cell-type deconvolution methods across cross-platform transcriptomic data, finding that log-normal regression methods like SpatialDecon perform most reliably.

Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation

The paper identifies tertiary lymphoid structures in gliomas as sites of immune response, showing they correlate with better survival and involve T and B cell clonal expansion and plasma cell formation.

Identification and characterization of tertiary lymphoid structures in brain metastases

The paper identifies tertiary lymphoid structures in brain metastases from different cancer types and links their presence to patient survival.

Modulation of the ATP-adenosine signaling axis combined with radiotherapy facilitates anti-cancer immunity in brain metastasis

This study shows that blocking ATP-to-adenosine enzymes and combining with radiotherapy improves anti-cancer immunity in brain metastases by altering immune cell populations and tumor inflammation.