Author

Aakanksha Singh

Goethe University FrankfurtORCID 0000-0002-0700-9441Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:deconvolution· 1

Frequent Co-Authors

Jadranka MacasiD· 2 shared Jennifer H. LuniD· 2 shared Jonathan Schupp· 2 shared Karl Heinz Plate· 2 shared Katharina ImkelleriD· 2 shared Pinar CakmakiD· 2 shared Yvonne ReissiD· 2 shared Eike SteidliD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioinformatics

Jadranka MacasORCID

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2 papers

Recent·Most cited

Benchmarking cell-type deconvolution in cross-platform transcriptomic data

Aakanksha Singh, Pinar Cakmak, Jennifer H. Lun, Jadranka Macas, Karl Heinz Plate, Yvonne Reiss, Jonathan Schupp, Katharina Imkeller

This study benchmarks cell-type deconvolution methods across cross-platform transcriptomic data, finding that log-normal regression methods like SpatialDecon perform most reliably.

Genome biology · Aug 13, 2026Peer-reviewedBioinformatics

Glioma-associated tertiary lymphoid structures are sites of lymphocyte clonal expansion and plasma cell formation

Pinar Cakmak, Jennifer H. Lun, Aakanksha Singh, Jadranka Macas, Jonathan Schupp, Jonas Schuck, Zeina Mahmoud, Miriam I. Köhler, Tatjana Starzetz, Michael C. Burger, Eike Steidl, Lucie Marie Hasse, Elke Hattingen, Karl Heinz Plate, Yvonne Reiss, Katharina Imkeller

The paper identifies tertiary lymphoid structures in gliomas as sites of immune response, showing they correlate with better survival and involve T and B cell clonal expansion and plasma cell formation.

Immunity · Oct 21, 2025Peer-reviewedImmunology