Hiutung Chu

This study shows that targeting catecholate siderophore systems reduces AIEC colonization in colitis by immunization, preserving gut microbiome composition.

The paper identifies alkamines as a previously hidden class of metabolites formed via reductive amination, revealing significant gaps in metabolomics and drug metabolism understanding.

The paper identifies microbial bile acid conjugation as a drug-activating function for 5-ASA, revealing its therapeutic relevance through metabolomics analysis.

This study identifies Escherichia coli as a key driver of B cell accumulation in Peyer's patches via CXCR2-dependent mechanisms involving curli amyloid fibers and TLR2 signaling.

This study identifies genetic factors enabling Bacteroides fragilis to transition from commensal to pathogenic by analyzing 813 strains and their genomic diversity.

This study compares the pangenome of Bacteroides fragilis genomospecies to reveal genetic diversity and ecological roles, finding division I and II strains represent distinct species with different functional adaptations.