Author

Jadson C. Santos

Universidade de São PauloORCID 0000-0001-7499-8975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:protein design· 2 Research Focus:protein structure prediction· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Geraldo Aleixo Silva PassosiD· 2 shared Eduardo Antônio DonadiiD· 1 shared Elvira Regina TamarozziiD· 1 shared Mariângela DamettoiD· 1 shared Rodrigo BonaciniD· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersBioinformatics

Geraldo Aleixo Silva PassosORCID

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2 papers

Recent·Most cited

BioinformaticsbioRxivPreprintSep 11, 2023

The high infectivity of the SARS-CoV-2 Omicron variant is associated with an exclusive S477N spike receptor-binding domain mutation

Jadson C. Santos, Elvira Regina Tamarozzi, Mariângela Dametto…·Geraldo Aleixo Silva Passos

This study uses molecular dynamics simulations to show that the Omicron variant's S477N mutation enhances spike-ACE2 binding, contributing to its higher infectivity compared to Delta.

DOI 10.1101/2023.09.11.557161

humanproteomics

𝕏 PostBluesky

BioinformaticsbioRxivPreprintDec 29, 2020

The high infectivity of SARS-CoV-2 B.1.1.7 is associated with increased interaction force between Spike-ACE2 caused by the viral N501Y mutation

Jadson C. Santos, Geraldo Aleixo Silva Passos

In silico mutagenesis and interface analysis indicate that the SARS-CoV-2 lineage B.1.1.7 Spike N501Y substitution increases intermolecular contacts with human ACE2 residues Y41 and K353.

90 citations

humanproteomics

𝕏 PostBluesky