Jeff L. Waugh

This paper uses fMRI to show that human striatal compartments, striosome-like and matrix-like, have distinct functional activation patterns during different phases of movement.

The paper shows that hippocampal projections to striatal compartments are spatially segregated, with CA1 preferentially targeting striosome-like regions in dorsal striatum and a small region targeting matrix-like regions.

This paper identifies striosome-like and matrix-like compartments in the human striatum using fMRI and shows their distinct activation patterns during working memory tasks.

This study identifies distinct resting state functional networks associated with striosome and matrix compartments in the human striatum using diffusion and functional MRI data.

The paper maps compartment-specific insulo-striate structural connectivity in humans, finding distinct biases toward striosome-like or matrix-like striatal compartments in specific insular subregions.

Chronic excitation of striatal cholinergic interneurons in mice induces clinically-relevant dystonic leg adduction variability, supporting their role in dystonia and suggesting therapeutic targets.

This paper investigates sustained fMRI BOLD signals in cervical dystonia patients after repetitive movement, finding abnormal activity in the putamen and cerebellum, and links these findings to cervical muscle function via sEMG.

This paper models GNAO1 mutations' effects on GPCR signaling to explain disease phenotypes and therapy responses in neurological disorders.