Bhooma R. Aravamuthan

This paper shows that hCG reduces inflammation-induced brain damage and neuron loss in a mouse model of neonatal hypoxia-ischemia.

The paper develops and validates an electronic informed consent platform for trio-based genomic research, showing high participant comprehension and satisfaction.

The paper evaluates the clinical impact of genetic findings in cerebral palsy, finding 8% of cases have actionable genetic diagnoses with moderate-high clinical utility.

This study develops a mouse model of preterm birth to investigate its link to dystonia and finds reduced cortical parvalbumin immunoreactivity in preterm mice.

Chronic excitation of striatal cholinergic interneurons in mice induces clinically-relevant dystonic leg adduction variability, supporting their role in dystonia and suggesting therapeutic targets.

The paper uses DeepLabCut to analyze limb positioning in mice after spared nerve injury (SNI) and finds motor phenotypes not related to pain.

This study examines striatal cholinergic interneuron numbers in a rodent model of dystonic cerebral palsy and finds they are increased, though not correlated with dystonia severity.