Author

Saptaswa Dey

University of GrazORCID 0000-0001-7532-7858Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Lukas KenneriD· 2 shared Michaela SchledereriD· 2 shared Boris TichýiD· 1 shared Christina SternbergiD· 1 shared Daniela ZwolanekiD· 1 shared Desiree Lindner· 1 shared Felix SternbergiD· 1 shared Gerda EggeriD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

Lukas KennerORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMar 3, 2025

Targeting the hyperactive STAT3/5 pathway in cutaneous T-cell lymphoma with the multi-kinase nuclear transporter inhibitor IQDMA

Saptaswa Dey, Helena Sorger, Michaela Schlederer…·Peter Wolf

This study evaluates IQDMA, a multi-kinase inhibitor, as a targeted therapy for cutaneous T-cell lymphoma, showing significant tumor volume reduction and STAT3/5 pathway inhibition compared to PUVA.

DOI 10.1101/2025.03.03.641168

mouseexperimental assay

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Cancer BiologyMolecular CancerPeer-reviewedOct 31, 2024

Cell-autonomous GP130 activation suppresses prostate cancer development via STAT3/ARF/p53-driven senescence and confers an immune-active tumor microenvironment

Christina Sternberg, Martin Raigel, Tanja Limberger…·Lukas Kenner

This study shows that activating GP130 in prostate epithelial cells suppresses tumor growth through senescence and immune activation, suggesting a new therapeutic approach.

17 citations

humanbulk RNA-seq

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