Molecular BiologybioRxivPreprint
A CROP-seq screen of histone modifying enzymes reveals histone demethylase Kdm5c regulates inflammatory macrophage activation.
Femke Horstman, Guillermo R. Griffith, Francesco Vinciguerra…·Koen H.M. Prange
The paper uses CROP-seq to identify histone modifying enzymes regulating inflammatory macrophage activation, finding Kdm5c modulates inflammatory responses by balancing baseline and inducible activation.