Author

Femke Horstman

Amsterdam University Medical Centers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Cindy P. A. A. van Roomen· 1 shared Francesco Vinciguerra· 1 shared Gerard PasterkampiD· 1 shared Guillermo R. GriffithiD· 1 shared Judith C. SluimeriD· 1 shared Koen H.M. PrangeiD· 1 shared Menno P.J. de WintheriD· 1 shared Michal MokrýiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Cindy P. A. A. van Roomen

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1 paper

Recent·Most cited

A CROP-seq screen of histone modifying enzymes reveals histone demethylase Kdm5c regulates inflammatory macrophage activation.

Femke Horstman, Guillermo R. Griffith, Francesco Vinciguerra, Ricky Siebeler, Cindy P. A. A. van Roomen, Tatyana Kuznetsova, Judith C. Sluimer, Gerard Pasterkamp, Michal Mokrý, Menno P.J. de Winther, Koen H.M. Prange

The paper uses CROP-seq to identify histone modifying enzymes regulating inflammatory macrophage activation, finding Kdm5c modulates inflammatory responses by balancing baseline and inducible activation.

bioRxiv · Oct 30, 2025 · PreprintMolecular Biology