Author
Maastricht University Medical CentreORCID 0000-0002-0269-4582Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Raúl Izquierdo-Serrano, Diana Sharysh, Vanessa Cumbicus…·Jacob Fog Bentzon
This study shows that loss of HIF1α in smooth muscle cells in atherosclerosis leads to oxidative stress, increased SMC proliferation, and plaque expansion.
Femke Horstman, Guillermo R. Griffith, Francesco Vinciguerra…·Koen H.M. Prange
The paper uses CROP-seq to identify histone modifying enzymes regulating inflammatory macrophage activation, finding Kdm5c modulates inflammatory responses by balancing baseline and inducible activation.
Charlotte J. Teunis, Lobke F. Zijlstra, Johannes H.M. Levels…·Nordin M.J. Hanssen
This study investigates the association between kynurenine and NAD+ pathway metabolites and macrophage content and polarization in carotid plaques, finding higher kynurenine levels correlate with M1 macrophages and reduced NAD+.
Tore Bleckwehl, Sidrah Maryam, Anne Babler…·Sikander Hayat
The paper integrates single-cell RNA-seq and spatial transcriptomics data to reveal cellular interactions and changes in human atherosclerosis.