Ryoji Fukabori

This paper develops a method to activate specific neurons in the mammalian brain using peripheral administration of ligand precursors, demonstrating its effectiveness in inducing neurotransmitter release and behavioral responses.

The paper characterizes TH-Cre knock-in rats generated via Combi-CRISPR, showing cell type-specific Cre expression and normal catecholamine metabolism and behavior.

This study shows that activating locus coeruleus norepinephrine neurons enhances aversive memory retrieval in mice.