Yu Zhang

This study develops an mRNA-LNP delivery system to program CAR-Ms in vivo, showing enhanced antitumor effects through immune activation and synergy with PD-1/L1 therapy.

The paper develops a human gene expression predictor to decode transcriptional regulation by modeling TF-target gene relationships across tissues and conditions.

EXPLICIT-Kinase predicts gene expression in Arabidopsis using kinase genes, identifying key regulators of pathways and showing conservation with maize.

The paper identifies disease-associated gene modules using a co-expression network from GTEx data, revealing molecular pathways for obesity, cardiomyopathy, and other diseases.