Author

Carolyn Kraus

University of Massachusetts Chan Medical SchoolORCID 0000-0001-7552-099XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Research Focus:perturbation response prediction· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Erik J. SontheimeriD· 2 shared Abbas Abdallah· 1 shared Abby V. McGeeiD· 1 shared Alireza EdrakiiD· 1 shared Amy B. GoodaleiD· 1 shared Audrey L GriffithiD· 1 shared Aydan KahrimaniD· 1 shared Berta Escude Velasco· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Erik J. SontheimerORCID

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2 papers

Recent·Most cited

GenomicsCell GenomicsPeer-reviewedMar 1, 2024

Modular vector assembly enables rapid assessment of emerging CRISPR technologies

Abby V. McGee, Yanjing V. Liu, Audrey L Griffith…·John G. Doench

The paper introduces a modular CRISPR vector assembly system called Fragmid, enabling rapid creation and testing of CRISPR technologies through combinatorial design and pooled screening.

12 citations

CRISPR screenexperimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedOct 21, 2022

CRISPR/Cas9-Mediated Excision of ALS/FTD-Causing Hexanucleotide Repeat Expansion in C9ORF72 rescues major disease mechanisms in vivo and in vitro

Katharina E. Meijboom, Abbas Abdallah, Nicholas P. Fordham…·Christian Mueller

This study removes a hexanucleotide repeat expansion in C9ORF72 using CRISPR/Cas9 in cell and animal models, reducing disease hallmarks.

72 citationstop 2%

mousehuman

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