Carlos Bueno

This study shows that direct reprogramming of human somatic cells into neurons involves a transient intermediate state, with cells exhibiting neuronal markers and functional properties.

This study shows human bone marrow-derived mesenchymal cells can transdifferentiate into neural-like cells without cell fusion, forming binucleated cells through nuclear movement.

This study shows that human adult stem cells differentiate into neural cells through a de-differentiation step followed by re-differentiation, confirmed by observing morphology changes and micronuclei movement.

This study investigates the morphological changes during neurogenesis in human periodontal ligament stem cells, revealing transient nuclear lobulation not linked to proliferation and similar to in vivo neurogenic niches.