Sean Michael Howard

This study shows that aging impairs mesenchymal stem cells by reducing osteogenesis, increasing adipogenesis, and decreasing mitochondrial mechanical responsiveness.

This study shows that low-intensity vibrations cause nuclear motion and cytoskeletal changes in mesenchymal stem cells, independent of matrix strain, leading to transcriptional activation.

This study investigates whether low-intensity vibration affects microtubule dynamics in vitro and finds no significant changes compared to controls, unlike Taxol treatment.

This paper develops and characterizes a low-intensity vibrational bioreactor for microgravity studies on the International Space Station.