Author

Zachary Knotts

Brandeis UniversityORCID 0000-0001-7557-1922Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Michael T. MarriD· 2 shared Meghan T. HarrisiD· 1 shared Nicholas K. Clark· 1 shared William B. DahliD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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2 shared papersMolecular Biology

Michael T. MarrORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintApr 21, 2026

Acute EIF4G1 depletion reveals transcript-wide determinants of initiation factor dependence and activates initiation-specific ribosome quality control

Zachary Knotts, Michael T. Marr

The paper acutely depletes EIF4G1 in human cells and identifies transcript-specific effects on translation and ribosome quality control.

DOI 10.64898/2026.04.17.719311

humanbulk RNA-seq

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Molecular BiologyMolecular and Cellular BiologyPeer-reviewedSep 19, 2023

The Insulin receptor and Insulin like growth factor receptor 5 UTRs support translation initiation independently of eIF4G1

Nicholas K. Clark, Meghan T. Harris, William B. Dahl…·Michael T. Marr

The paper shows that the 5' UTRs of Insr and Igf1r transcripts support translation initiation independently of eIF4G1 in both in vitro and cellular settings.

4 citations

statistical modelexperimental assay

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