Molecular BiologybioRxivPreprint
Structure-informed mutagenesis identifies a conserved region critical for mouse insulin receptor 5'UTR IRES function
William B. Dahl, Tammy C. T. Lan, Silvi Rouskin, Michael T. Marr
DOI 10.1101/2024.11.05.622145
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Brandeis UniversityORCID 0000-0001-9918-5938Unclaimed ORCID profile · follow to get notified of new preprints
2 papers
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William B. Dahl, Tammy C. T. Lan, Silvi Rouskin, Michael T. Marr
Nicholas K. Clark, Meghan T. Harris, William B. Dahl…·Michael T. Marr
The paper shows that the 5' UTRs of Insr and Igf1r transcripts support translation initiation independently of eIF4G1 in both in vitro and cellular settings.