Molecular BiologybioRxivPreprint
Hepatic fructose metabolism is antagonized by growth hormone/insulin-like growth factor signaling via regulation of ketohexokinase expression
Salaheldeen Elsaid, Prathibha Meesala, Youngshim Choi…·Sui Seng Tee
This study identifies GH/IGF-1 signaling as a regulator of KHK expression, limiting fructose metabolism in the liver and contributing to MASLD.
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