Jurgen Kriel

SpaMTP integrates spatial metabolomics and transcriptomics data through a comprehensive analysis pipeline and visualization tools.

This paper introduces a workflow for integrating spatial transcriptomics and metabolomics data to analyze glioma tissue, identifying novel biological features at the tumor's infiltrating edge.

This paper uses 3D imaging to show that M. tuberculosis ESX-1 affects granuloma architecture in infected mice.

The paper compares the neutrophil response to Mycobacterium tuberculosis infection between HIV+ individuals with and without TB history, finding distinct gene expression and NETosis patterns in those without TB.

The paper introduces MEL, a method to quantify mitochondrial fission, fusion, and depolarisation in 3D time-lapse sequences, showing these events occur mainly at network branches and periphery in treated cells.